NSU student creates app for recognition, digitization and analysis of classical Tibetan texts using machine learning

Translation. Region: Russian Federal

Source: Novosibirsk State University –

An important disclaimer is at the bottom of this article.

A system for automatic recognition and transliteration of texts in classical Tibetan, focused on old printed documents made using Tibetan syllabic writing, which goes back to the ancient Indian Brahmi script, was created by a student of the Fundamental and Applied Linguistics program working at the Institute of Mathematics and Mathematical Geophysics of the Siberian Branch of the Russian Academy of Sciences. Humanitarian Institute of Novosibirsk State University Anna Murashkina. In her research, she used images of pages of classical Tibetan texts from the 18th-20th centuries from the archive of the Center for Oriental Manuscripts and Xylographs of the Institute of Mongolian, Buddhist and Tibetan Studies of the Siberian Branch of the Russian Academy of Sciences.

— The relevance of my work is due to the need to preserve and make digitally accessible the Tibetan cultural heritage, presented in the form of many historical manuscripts. Old printed documents, manuscripts and xylographs contain unique information about philosophy, religion, medicine, history and art, playing a key role in the study of the cultural traditions of the region. This knowledge is passed down from generation to generation in Tibet. However, over time, under the influence of natural and anthropogenic factors, paper media are subject to physical destruction, which leads to the loss of priceless information and limits access to these unique materials. Currently, the Tibetan Fund of the Institute of Mongolian, Buddhist and Tibetan Studies of the Siberian Branch of the Russian Academy of Sciences contains up to 70 thousand units of chronicles that are at risk of being lost. One of the most reliable ways to preserve and systematize historical documents is to digitize them, — said Anna Murashkina.

The young researcher set herself the task of using machine learning to build a model that would recognize Tibetan alphabet symbols from images, translate them into machine-readable form, and at the same time show greater accuracy than existing open solutions, including Tesseract.

— To do this, I manually performed linguistic markup of Tibetan text lines from the IMBT SB RAS collection. Then, taking into account the specifics of Tibetan graphics, I developed a system for assessing the quality of optical character recognition (OCR). Then I compared existing architectures and chose a convolutional neural network model, which required additional training, — explained Anna Murashkina.

She implemented additional training of the model on a marked corpus of documents, and as a result, a complete modular OCR algorithm was created, including the stages of pre-processing, segmentation, recognition and post-processing.

— For me, the value of the project is that I helped digitize an archive that stores history — documents created by people of the past who wanted to pass on their knowledge to future generations. I am glad that I am helping to transfer this knowledge through time, preserve it and make it available to a wider audience. My development will be used by employees of the Institute of Mongolian, Buddhist and Tibetan Studies of the Siberian Branch of the Russian Academy of Sciences. The possibility of cooperation with the Buddhist Center for Digital Technologies, which digitizes the archives of temples and monasteries, is also being discussed. In cooperation with this organization, we will expand the possibilities of digitizing Tibetan manuscripts using open resources developed jointly with researchers from organizations in different countries, so that later everyone can touch this priceless heritage and get acquainted with the documents that are in temples and archive repositories, — said Anna Murashkina.

Material prepared by: Elena Panfilo, NSU press service

Please note: This information is raw content obtained directly from the source of the information. It is an accurate report of what the source claims and does not necessarily reflect the position of MIL-OSI or its clients.

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NSU scientists create a new type of endoscopic system for diagnostics and destruction of cancer cells

Translation. Region: Russian Federal

Source: Novosibirsk State University –

An important disclaimer is at the bottom of this article.

The results of the Russian Science Foundation mega-grant competition for fundamental scientific research and exploratory scientific research under the supervision of leading foreign scientists have been summed up. 230 projects from 127 scientific organizations from 35 subjects of the Russian Federation applied for RSF support. The projects submitted for the competition are being implemented under the supervision of leading scientists with citizenship from 40 countries, including China, India, Iran, Belarus, Kazakhstan, the USA, Italy, and France. According to the results of the examination, 14 projects were declared winners. For 5 years, they will receive from 20 to 50 million rubles annually. If necessary, it is envisaged to extend the grant support for another three years.

Among the winners is the project of scientists from the Laboratory of Nonlinear Optics of Waveguide Systems of Novosibirsk State University "The Kerr Self-Cleaning Effect of Multimode Beams in Specialized Optical Fibers and Its Application for Biomedicine". This laboratory was created in May 2017 as a result of the victory of the project "Spatio-temporal Nonlinear Optics of Multimode and Multi-Core Fiber Systems" in the fifth competition of the Ministry of Education and Science of Russia for receiving grants from the Government of the Russian Federation for state support of scientific research conducted under the supervision of leading scientists. Its head is a recognized world expert in the theory of surface waves, as well as an expert in nonlinear effects in fiber-optic communication systems Stefan Wabnitz. His research activity for more than 30 years took place in leading academic and industrial institutions in Europe and the USA.

— Our project is aimed at creating an innovative endoscopic device that combines optical biopsy and low-temperature plasma therapy technologies. Its goal is to develop a unified system that provides the ability to both diagnose and treat gastrointestinal diseases, including oncological diseases, in real time, which will eliminate the need for lengthy histopathology and increase the accuracy of examinations. This device will combine two functions at once — diagnostics (using machine learning) and therapy (laser/plasma), minimizing damage to healthy tissues, — said Denis Kharenko, senior researcher at the laboratory.

In current medical practices, ex vivo histopathology is used for accurate cancer diagnostics, during which laboratory studies of living tissue transferred from the body to an artificial external environment are carried out. It involves taking tissue from the patient, which leads to delays in the start of therapy and requires complex laboratory procedures and practically does not allow observing the course of the disease in dynamics. NSU scientists propose to solve this problem by introducing in-vivo diagnostics, which allows examining the body without taking material using optical endoscopic methods. It is important that this diagnostic method will be associated with the possibility of therapeutic intervention, which will not only significantly increase the area under study and the volume of data obtained, but also accurately identify the affected area during repeated examination, minimizing time and economic costs, as well as the risks of errors associated with the analysis of samples outside the body.

— The new type of endoscopic system we are creating, in addition to diagnostics, will be able to precisely affect tumor cells using temperature-controlled laser radiation and low-temperature plasma, causing their apoptosis without excessive heating — a process of programmed cell death, in which the cell self-destructs, disintegrating into individual fragments, which are then absorbed by other cells without causing negative consequences. This leads to minimal damage to healthy tissue. This feature will reduce side effects, avoid fibrosis and vascular damage, which is extremely important for improving the quality of life of patients. The project is a significant step forward in the field of "optical biopsy" and endoscopic therapy, — explained Denis Kharenko.

One of the main scientific tasks of the scientists will be to optimize the process of diagnostics and treatment of cancer using a multimode optical fiber, which implements the Kerr self-cleaning effect, providing high resolution (up to 0.66 µm) and resistance to mechanical impacts during the propagation of laser radiation. The integration of multiphoton fluorescence and Raman scattering will further expand the diagnostic capabilities of the device, allowing for spectroscopic studies of tissues and the detection of biomarkers characteristic of different stages of the disease with microscopic accuracy. According to the project participants, this technology will make the device a universal tool for both diagnostics and subsequent treatment.

The project involves several stages. First, the scientists will design and test multimode fibers and high-repetition-rate lasers for the endoscopic system. The next step will be to test the device on biological samples, including lab-created organoids and cancerous tissue.

— We are confident that our experimental setup with the ability to precisely control low-temperature plasma will allow localized impact on the affected areas of organs and tissues, which will create the basis for the application of the technology in clinical practice. We intend to create a flexible and highly effective visualization and therapy system, which will subsequently become established as a standard in the field of diagnostics and treatment of gastrointestinal diseases, including oncological diseases in the early stages, — said Denis Kharenko.

Material prepared by: Elena Panfilo, NSU press service

Please note: This information is raw content obtained directly from the source of the information. It is an accurate report of what the source claims and does not necessarily reflect the position of MIL-OSI or its clients.

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"Kimberlite Magic": NSU postgraduate student Alexey Tarasov became a laureate of the RAS medal for the study of deep mantle melts

Translation. Region: Russian Federal

Source: Novosibirsk State University –

An important disclaimer is at the bottom of this article.

The Russian Academy of Sciences has announced the winners of the 2024 competition for medals with prizes for the best scientific works of young scientists and students. One of the laureates was a postgraduate student Faculty of Geology and Geophysics (FGG) of NSU Alexey Tarasov. He received the award in geology, geophysics, geochemistry and mining sciences for his research on melt inclusions in minerals of mantle peridotite xenoliths.

We talked to Alexey about his scientific path, research topic, participation in the competition and plans for the future.

— How did you end up at NSU?

— I entered NSU in 2018 after finishing school in Barnaul, based on the results of the Unified State Exam. I studied for a bachelor's degree at the Faculty of Geography and Geography, then entered the master's program. Now I continue my studies in graduate school.

— Why did you choose the Faculty of Geology and Geophysics?

— I have been interested in minerals since childhood, I had a small collection at home. I attended the "Young Geologist" club — there was one in Barnaul. Gradually, my hobby turned into a professional interest. I knew that Novosibirsk had a strong school in geochemistry, and this played a decisive role. There was no doubt where to go.

— Tell us about your scientific work for which you received the Russian Academy of Sciences medal.

— The overall goal of all our work is to understand how diamond deposits are formed. Diamond is a form of carbon that is stable only under very high pressure, so it forms deep in the mantle, at depths of 150–160 kilometers and more. Most diamonds formed more than 2.5 billion years ago and are still in the mantle because it is too deep to mine them.

But there are kimberlite magmas. They form in the mantle and, unlike most other magmas, rise to the surface very quickly. In doing so, they take with them fragments of mantle rocks – so-called xenoliths, and minerals – xenocrysts. Sometimes – with diamonds.

When magma reaches the surface, it forms kimberlite pipes, which are the main source of diamonds in nature. But what is kimberlite magma? What it consists of, where it comes from, and under what conditions it originates – is still not exactly known. This is a key scientific question, and I am working on solving it.

– How do you research this?

— I study melt inclusions in xenolith minerals. These are tiny drops of magma that were “sealed” in crystals during their growth and preserved in their original form. These inclusions provide a unique opportunity to reconstruct the composition of kimberlite melts at the moment of their origin — before all the changes and contaminations that occur during their ascent to the surface.

The composition of these inclusions can tell us about the temperature and pressure of formation, and the type of rock from which they formed. This helps us get closer to understanding where and how new kimberlite pipes can form, and therefore potentially predict where diamonds can be found.

— What, in your opinion, helped you receive the RAS medal?

— It’s hard to say how exactly the selection took place. But I think several factors played a role. I tried to show that my work was not just fundamental, but also had potential applied significance. In addition, at the time of application, I had six published articles in which I was the author or co-author.

But, to be honest, the main thing is not "what", but "who". My scientific supervisor Alexander Viktorovich Golovin. He insisted that I participate in conferences, helped with writing articles, tolerated my mistakes, demanded high quality. It was he who convinced me to apply for the RAS competition. In addition to him, other colleagues at the institute and teachers at the faculty supported me. Without them, nothing would have happened.

— How did the competition itself go?

— It was quite simple: you had to prepare an application, attach a research paper (in my case, it was a master's thesis), provide a list of publications, and sign documents. There were no in-person stages — everything was done in writing.

— What are your plans next?

— I am continuing my postgraduate studies and working at the Institute of Geology and Mineralogy of the Siberian Branch of the Russian Academy of Sciences. I plan to defend my PhD thesis in 2027. I am currently finishing my first article, where I am the first author, and I want to publish it in a foreign journal of the 1st–2nd quartile. I already sent it six months ago, but was rejected. The reviewers pointed out the weak discussion and insufficient English.

Now I am rewriting the text, looking for a translator and funding for professional translation. In parallel, I am working on the following articles. My supervisor has set a task – five articles by the end of my postgraduate studies. To be honest, I am not sure that I will cope, but I will make every effort.

The Russian Academy of Sciences holds an annual competition for medals and prizes for young scientists and students. In 2024, 21 young scientists and 21 students received awards. Each laureate receives a medal, a diploma, a badge, and a cash prize of 100,000 rubles for young scientists and 50,000 rubles for students.

The competition covers key areas of natural, technical and human sciences and is held with the aim of encouraging young scientists, supporting professional growth and enhancing the prestige of research activities.

We congratulate Alexey Tarasov on his well-deserved award and wish him success in his future scientific research!

Please note: This information is raw content obtained directly from the source of the information. It is an accurate report of what the source claims and does not necessarily reflect the position of MIL-OSI or its clients.

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New technology for restoring gas turbine engine blades patented at Novosibirsk State University

Translation. Region: Russian Federal

Source: Novosibirsk State University –

An important disclaimer is at the bottom of this article.

Employees Competence Center of the National Technology Initiative (NTI) in the direction of "Modeling and development of new functional materials with specified properties" based at NSU developed an innovative method for restoring damaged turbine blades of engines for aviation and energy (gas turbine units). The technology was developed with financial support from the NTI Foundation, successfully patented and is already beginning to be implemented in practice.

Leading researcher of the NTI Center of Novosibirsk State University, head of the laser technology laboratory of the Institute of Theoretical and Applied Mechanics of the Siberian Branch of the Russian Academy of Sciences, Doctor of Engineering Alexander Malikov spoke in detail about the essence of the development and the prospects for its implementation:

— Our new method allows us to restore heavily worn sections of gas turbine blades, fully preserving the original performance characteristics of the product. To do this, we use a special mode of laser pulse-periodic action, which allows us to form strong protective layers of metal or ceramic composites on the surface.

According to Alexander Malikov, the task was to restore the thin edges of the blades, which are subject to intense exposure to high temperatures and pressure during engine operation. The advantage of the proposed technology is that using the traditional surfacing method would lead to overheating and destruction of sensitive areas of the parts.

"We proposed an original solution to the problem by preliminary forming special protective layers before the main stage of surfacing. This approach allowed us to preserve the original geometric shape of the blade and ensure reliable adhesion of the restored layer to the main structure," the scientist explained.

The new method significantly reduces the cost of repairs, ensuring high strength and durability of restored elements of gas turbine units.

The developed technology is in high demand on the Russian energy generation and aircraft manufacturing market. Modern gas turbine engines are used everywhere – from civil aviation to electric power engineering and natural gas transportation.

Alexander Malikov noted the importance of this area of research:

— The production of high-quality blades is one of the ten key technologies of the modern world. Their production requires complex solutions due to extreme operating conditions. Only four countries in the world have the necessary competencies: the USA, Great Britain, France and Russia.

Previously, the energy segment of the Russian market was heavily dependent on foreign suppliers of spare parts and services for the restoration of parts. With the departure of Western companies from the Russian market, there was a need to develop our own technologies and services capable of replacing foreign analogues. The new technology created by Novosibirsk scientists is capable of significantly increasing the reliability and cost-effectiveness of servicing large industrial enterprises and facilities using gas turbine units.

In the near future, it is planned to introduce the technology into serial production; a number of Russian companies have shown interest in it. Meanwhile, researchers continue to develop technologies for the restoration of various types of blades and other elements of industrial equipment.

— To solve problems of this type, we first need to carefully study the properties of the material from which the product is made at the atomic level. In our work, we use synchrotron radiation, which provides great opportunities for emitting phase composition at a very high resolution level, and if we know the exact phase states of the material, the structural phases, then we can control it, — explained Alexander Malikov.

Scientists will have even more opportunities with the launch of the Siberian Ring Photon Source (SKIF), at one of whose workstations a number of studies in this area are already planned.

Please note: This information is raw content obtained directly from the source of the information. It is an accurate report of what the source claims and does not necessarily reflect the position of MIL-OSI or its clients.

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NSU student develops software for configuring SKIF accelerator

Translation. Region: Russian Federal

Source: Novosibirsk State University –

An important disclaimer is at the bottom of this article.

As is known, SKIF is a mega-science facility that has become the first in Russia and the most powerful source of fourth-generation synchrotron radiation in the world. This complex opens up the broadest possibilities for research in a variety of fields – from materials science to medicine. Due to the high brightness and coherence of the radiation, SKIF allows you to literally "look inside" a substance, obtain ultra-precise data on its structure and behavior. The implementation of such projects significantly strengthens Russia's position in international scientific cooperation and creates a technological base for breakthrough developments in science-intensive industries.

The program created by Vladislav is a configuration database. It stores information about the accelerator devices and allows it to be automatically transferred to the control systems.

— Essentially, this is a description of a number of parameters of SKIF devices, which is then transferred to the control software. That is, my program provides other programs with up-to-date data for working with the accelerator hardware, — says Vladislav Rodyakin, a bachelor's degree graduate Physics Department of NSU.

The work on the program became Vladislav's final qualification work. He did it as part of a team of employees of the Institute of Nuclear Physics SB RAS, which is responsible for the automation of processes in the SKIF project and other Russian accelerators. The software was developed from October to May and took about 20 hours a week for several months. Now Vladislav continues to support and improve his system based on requests received during operation.

— I especially liked that working at INP gave me real independence. I went through the whole cycle — from database design to creating an interface, web application and integration into the management system. This is a unique experience: in the business industry, novice programmers often get routine tasks, but here I worked like a one-man band, — he notes.

Close cooperation between the scientific institutes of the Siberian Branch of the Russian Academy of Sciences and Novosibirsk State University has continued throughout the history of the university. This approach allows students to get involved in real research and engineering projects already at the stage of study. And the project completed by Vladislav is a vivid confirmation of this.

— Our program at the NSU Physics Department specifically prepares students to work with scientific installations and write software for them. In my third year of study, I took a course whose teacher was working on software for SKIF — he invited me to join the team. That’s how I ended up in a large scientific project, — says Vladislav.

Today, Vladislav Rodyakin continues his studies in the Master's program and works at the Institute of Nuclear Physics. His experience shows that a university can be not only a place of study, but also a launching pad for participation in advanced projects of national and international scale.

Please note: This information is raw content obtained directly from the source of the information. It is an accurate report of what the source claims and does not necessarily reflect the position of MIL-OSI or its clients.

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NSU Startup Studio Presented Its Projects for the First Time in the Form of the Artificial Intelligence Alley

Translation. Region: Russian Federal

Source: Novosibirsk State University –

An important disclaimer is at the bottom of this article.

The Alley of Friendship of Artificial and Natural Intelligence was a horizontal space designed as a real alley: it had trees and a waterfall, and an interactive exhibition was inscribed into such a landscape. The alley symbolized a walk of an ordinary person through the world of artificial intelligence and modern technologies that are available on the market and that can be tried right here and now. In total, over 1,000 people walked through the alley during the day of work – from 10 a.m. to 6 p.m.: each of the visitors got involved in the interactive activities presented at the stands. A separate bright component of the exhibition was the game "Startup Race", which the NSU Startup Studio presented to a wide audience and tested in action.

The alley included the following technologies and developments:

1. Emotion analyzer

At the reception for registering guests of Smart Picnic there was a special camera with an interactive screen. Anyone could come up, make a face, and the screen would display the emotion they were experiencing.

The guests were particularly impressed by this invention: everyone had fun and amusement checking how well their faces were able to express emotions. The technology also has medical applications for diagnosing diseases associated with incorrect display of emotions on the face.

2. Virtual assistant

After the first stop, guests were met by a virtual animator from the NSU Startup Studio, who announced all the technologies created using artificial intelligence.

3. Emulator of human personality in voice

NSU students who received a grant created a voice simulator that imitated the personality of famous people. Visitors to the alley interacted with the simulator through their voice, trying to sell it a pen or ask a question, like in the movie "The Wolf of Wall Street."

4. Smile analyzer

The next stand was a smile analyzer, developed jointly with a doctor from the Rostov Medical University. The device, using a patented method, gave recommendations on the health of teeth and the oral cavity based on a smile analysis.

5. Game "Academ Dreams"

This stand offered to immerse oneself in the world of Akademgorodok in the late 1990s and early 2000s. Players could become virtual residents of the science town and interact with its inhabitants, creating a copy of themselves in the virtual space.

6. Swaid Monitor

It was a photoplethysmograph that recorded heart rate readings and constructed a stress index using the Baevsky method. Together with the staff of the Psychology department of the Institute of Medicine and Medical Technologies of NSU, the game "Calm Down" was developed, in which participants put on a bracelet and, while meditating, watched the stress line decrease on the screen. The monitor helped participants achieve a meditative state even in a crowd.

7. Map of emotions

Each of the visitors to the alley and the Picnic sites in general could mark themselves on the map and indicate what emotion they are currently experiencing in real time. The development is also intended for deep behavioral research: for example, what emotion and how intensely a particular group of people in a particular location experiences.

8. Games with artificial intelligence

Several separate stands presented interactive games in which visitors fought against AI – "Crocodile" and "Riddles". Separately, an interactive demo board was presented with photographs of how people interact with inventions at the exhibition.

9. Game "Startup Race"

The development was first presented at the alley and was tested in real time.

Of course, not all projects of the NSU Startup Studio were presented at the Alley, since among its participants there are more than 30 residents with their own ideas and projects.

— The Artificial Intelligence Exhibition became a kind of "frontier" for us, which could be organized at the Smart Picnic site. On the one hand, the alley became our product and even an element of the interactive show, and, on the other hand, it was also a challenge for our residents and partners — they had to show their technology to people in extreme conditions and, despite everything, think through to the smallest detail how to present a demo version of the product, what to say in the opening speech, at what points it is worth speeding up production in order to show a finished product, and not just developments and an idea. That is, the Artificial Intelligence Alley became a powerful incentive for our residents to work, — said Evgeny Ivanov, a representative of the NSU Startup Studio and managing partner of the Coion investment syndicate.

According to Evgeniy, some startups actually showed high growth rates thanks to their participation in the Alley.

— One of the projects, Lexis Voice, the very same stand with a voice imitator and the question "Sell a pen", showed a good result. The team accelerated in all directions, from development to sales market. Thus, in a month and a half, the project's revenue increased 5 times, because there was a strict deadline – participation in the exhibition, and a clear understanding of what should be ready by this time, — summed up Evgeny Ivanov.

The next step in popularizing innovative entrepreneurship after the Artificial Intelligence Alley is the Startup Unit school, which started in July, where anyone can feel like a budding entrepreneur. After the school, in the fall, all students will be able to start the NSU acceleration program .catalyst, and residents of the NSU startup studio will also be able to take part in the Siberian Venture Fair, where they will present projects in the format of idea boards. The goal of all these projects is one – to bring to life the ideas and developments of students.

— The fair is really one of the elements of the chain, which the Startup Studio is developing with its residents. Ultimately, all this is so that innovators launch some product, a viable business, and then return to the state the resources that are invested in them in the form of various subsidies, grant support that they can attract. Our task is for our residents to “spend” these funds correctly and as a result, a finished product is obtained that is needed by someone and will be sold, — emphasized Alexey Starostin, Director of the NSU Startup Studio.

Material prepared by: Tatyana Ershova, NSU press service

Please note: This information is raw content obtained directly from the source of the information. It is an accurate report of what the source claims and does not necessarily reflect the position of MIL-OSI or its clients.

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New molecular engineering laboratory created at NSU

Translation. Region: Russian Federal

Source: Novosibirsk State University –

An important disclaimer is at the bottom of this article.

In the structure Institute of Medicine and Medical Technologies (IMMT) NSU A new laboratory of molecular engineering has been created; it will become the first specialized laboratory beyond the Urals that will comprehensively deal with such promising areas of modern medicine as the cultivation of microorganism cells, the study of virome and metagenomic analysis, and the prediction of protein structure based on the analysis of the data obtained.

In early 2026, after the delivery of the new building of the NSU IMMT, which is part of the second stage of the NSU campus, built within the framework of the national project "Youth and Children", the laboratory will be located on the premises of the new campus. The creation of the laboratory is part of the strategic project "Center for the Integration of Personalized Biomedicine, Pharmacy and Synchrotron, Binary Technologies", financed within the framework of Priority 2030 programs.

Currently, the laboratory employs 5 people, including representatives of leading research centers in Novosibirsk and Tomsk. Also, students, postgraduates and graduate students of the Institute of Medicine and Medical Technologies, the Faculty of Natural Sciences and other faculties of NSU will be involved in the work in the laboratory, who, as part of the preparation of their diploma and scientific papers, will participate in the implementation of the laboratory's projects. The laboratory is headed by Elena Prokopyeva, PhD in Biology, research fellow at the IMMT NSU.

The laboratory is fully focused on solving applied problems facing the modern pharmaceutical industry and biomedicine. First of all, we are talking about the rapid implementation of new methods of pharmaceutical development, expansion of interdisciplinary research, integration of artificial intelligence and big data analysis in biology and medicine; as well as the formation of a modern educational environment for training new generation specialists, including students from different countries.

The main areas of work of the laboratory:

creation and improvement of biotechnological protocols for cultivating prokaryotic and eukaryotic microorganisms in laboratory and industrial bioreactors; creation of innovative methods for identifying and quantitatively analyzing viral particles using accelerator mass spectrometry; study of the diversity, structure and dynamics of viral communities (virosphere) in various ecological niches using modern methods of metagenomics and bioinformatics.

— One of the promising areas for the laboratory is the analysis of viromes (a set of viruses) using metagenomic and bioinformatics analysis in partnership with research institutes of the Siberian Branch of the Russian Academy of Sciences. This is an advanced area in science. Metagenomic analysis is based on next-generation sequencing methods, which can be used to “read” several sections of different genomes in different samples at the same time. However, today the problem is the analysis of billions of available sequences, the number of which increases exponentially every year. Thus, advanced technologies will speed up the process of identifying new viruses, even based on already available and published metagenomic data, — said Elena Prokopyeva.

The lab plans to use machine learning models to analyze biomedical data, such as genomic, transcriptomic, and proteomic data, as these methods can effectively identify complex patterns and relationships in large and multidimensional data sets. The use of machine learning in biomedical research opens up new opportunities for deep understanding of biological processes and improving clinical practice.

Another area of the laboratory's work is education. By the end of 2025, an interactive educational web application will be finalized. HTTP: //histology. HSU.ru, which includes a collection of digital microscope slides on histology, embryology and cytology.

— Thus, this project will create a comprehensive scientific and technical platform that will unite disparate areas (bioreactors, metagenomics, molecular diagnostics, digitalization of education and biomedical developments) into a single ecosystem, increase the efficiency of research and accelerate the introduction of innovations in industry and medicine, — Elena Prokopyeva emphasized.

The industrial and scientific partners of the laboratory are industry leaders — Technoprom LLC, research institutes of the SB RAS (G.I. Budker Institute of Nuclear Physics SB RAS, G.K. Boreskov Institute of Catalysis SB RAS, Federal Research Center Institute of Cytology and Genetics SB RAS), FBSI SRC VB Vector of Rospotrebnadzor, Federal Research Center for Fundamental and Translational Medicine (FRC FTM). The laboratory also cooperates with foreign partners, such as Qinghai University and East China Normal University (China), RSE Institute of Genetics and Physiology (Kazakhstan).

Please note: This information is raw content obtained directly from the source of the information. It is an accurate report of what the source claims and does not necessarily reflect the position of MIL-OSI or its clients.

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