Translation. Region: Russian Federal
Source: Novosibirsk State University –
An important disclaimer is at the bottom of this article.
From August 18 to 22, 2025, the All-Russian scientific conference with international participation "Modern Problems of Organic Chemistry" (SPOKh-2025) was held in the Akademgorodok of Novosibirsk. It was dedicated to the 100th anniversary of the birth of Corresponding Member of the USSR Academy of Sciences V.P. Mamaev. Maria Sotnikova, a 4th-year student, gave an oral report at the section dedicated to modern trends in biochemistry and analytical chemistry. Faculty of Natural Sciences of NSU, direction "Chemistry". Her scientific supervisor is a junior researcher at the Laboratory of Molecular Engineering Institute of Medicine and Medical Technologies (IMMT) NSU Nikita Basov.
The work presented by Maria is devoted to exometabolomic screening of yeast strains isolated from traditional fermented products – kumiss, mead and kefir fungus. Such analysis allows to identify microorganisms with unique metabolic profiles, promising for use in biofermentation tasks.
Modern analytical methods played a key role in the study: high-performance liquid chromatography combined with tandem mass spectrometry (HPLC-MS/MS). These technologies allow for the simultaneous recording of hundreds of metabolites and open up new possibilities in selecting strains for the synthesis of target substances in demand in industry, medicine, pharmaceuticals, and the agricultural sector.
The results showed that even closely related yeast strains can differ significantly in their metabolic profiles. This makes metabolomic analysis a powerful tool for rational selection of microorganisms for biotechnology and the development of environmentally friendly production.
M.A. Sotnikova's speech at the SPOH-2025 conference aroused great interest among the scientific community and became a vivid example of how NSU students and young researchers are forming a scientific foundation in the field of advanced biotechnology.
The work is especially important because it was carried out by young scientists and students working at IMMT NSU. In addition, Maria is already preparing her first scientific article dedicated to metabolomic studies of cells. Next year, she plans to enroll in a master's degree program in Industrial Pharmacy at IMMT NSU and continue her research at the intersection of analytical chemistry, biotechnology and medicine.
This is not the first time the student has performed: earlier, Maria was awarded a third-degree diploma at the International Scientific Student Conference (ISSC-2025), which was held at NSU for the 63rd time, in the Analytical Chemistry section.
Thus, at the university, students are involved in real science already at the early stages of their studies, participating in interdisciplinary projects at the intersection of chemistry, biology, medicine and engineering. It is this approach that meets the modern challenges of biofermentation and opens up prospects for the creation of future technologies.
The study was carried out in collaboration between the Laboratory of Molecular Engineering of the Institute of Mathematics and Mathematics of NSU and the Engineering Center "Prombiotech" of the Altai State University.
The project was implemented with the support of the Priority 2030 strategic academic leadership program.
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