Translation. Region: Russian Federation –
Source: Peoples'Friendship University of Russia
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Ekaterina Gosteva, Associate Professor of the Department of Nanoelectronics and Microsystems Engineering at RUDN University, is leading an interdisciplinary project to develop a technology for nanostructuring implant surfaces. Her goal is to make implant engraftment fast, reliable, and accessible to a wide range of patients.
The problem of dental implant rejection often stems not from the material, but from the implant's surface. Traditional processing methods, such as sandblasting, can leave microscopic contaminants that cause inflammation. A team of RUDN University scientists proposes a different approach.
"The project's goal is to create the most suitable surface that will help solve problems such as the inability to use implants in diabetics," says Ekaterina Gosteva, PhD in Physics and Mathematics and the project's leader.
What is the secret of the technology?
The new technique combines electrochemical etching in gentle solutions and precise laser irradiation. This combination allows for the precise creation of a specific microrelief on the titanium surface, ideal for bone fusion.
Advantages:
Absolute purity: eliminates the risk of surface contamination with abrasive or chemical residues; creates a uniform and controlled microrelief and adapts to the complex geometry of the implant; and enables personalization: the technology paves the way for the creation of implants with surfaces tailored to the individual bone characteristics of the patient.
From idea to prototype
Work on the project began in 2021 at the request of a Russian implant system manufacturer seeking to improve product performance.
"We've done extensive research into implant systems in Russia and around the world, identifying their strengths and weaknesses. This was necessary to further understand the methods and technologies used to process implants, the challenges manufacturers face, and how they can be addressed by understanding the processes occurring at the interface between the implant and the living environment," said Ekaterina Gosteva.
Now, with the support of a grant from RUDN University, the project has entered its active experimental phase. Funds have been used to purchase the necessary equipment and conduct experimental research.
"We've received four series of samples with varying surface design parameters and are now moving on to testing on model objects. A positive result will allow us to identify the 'ideal implant' and, by the end of the project, move on to scaling the technology and transferring it to production by 2028," said Ekaterina Gosteva.
The immediate goal is to conduct a series of biological tests (in vitro and in vivo) to prove the high biocompatibility of the created surfaces. A patent application is planned for the spring of 2026.
Partnership and the path to the clinic
The project's key partner is Licostom. The company plans to acquire the patents and technology in the future.
The associate professor sees a clear path for the development's implementation: after successful testing, the technology will be integrated into the partner's production lines. This will allow for the introduction of a new generation of Russian implants to the market in the foreseeable future, offering competitive pricing and improved properties.
The technology's potential extends beyond dentistry. The principles of controlled nanostructuring of surfaces are also in demand in other areas of medicine.
"We've already been approached by endoprosthesis manufacturers, and their needs involve not only surface shaping but also reducing the weight of the implant itself. I believe there are still many challenges in this area that require an interdisciplinary approach and the implementation of new technologies," says Ekaterina Gosteva.
Please note: This information is raw content obtained directly from the source. It represents an accurate account of the source's assertions and does not necessarily reflect the position of MIL-OSI or its clients.