Translation. Region: Russian Federation –
Source: United Nations – United Nations –
An important disclaimer is at the bottom of this article.
December 4, 2025 Healthcare
The World Health Organization (WHO) released its annual report on Thursday malaria, which notes significant progress in the fight against this disease thanks to the introduction of new tools—from vaccines to innovative mosquito nets. Experts estimate that by 2024, approximately 170 million cases of malaria infection and at least one million deaths will have been averted globally.
Since 2021, when the world's first malaria vaccine was approved, 24 countries have included it in their national immunization programs. Seasonal chemoprophylaxis has been expanded, reaching 54 million children in 2024, up from only 200,000 in 2012. Furthermore, the WHO has certified 47 countries and one territory as malaria-free. Cabo Verde and Egypt will join them in 2024, and Georgia, Suriname, and Timor-Leste will follow in 2025.
Despite these successes, in 2024, 282 million malaria cases and 610,000 deaths were recorded globally. Ninety-five percent of deaths occurred in the WHO African Region, with the majority of deaths occurring in children under five. The mortality rate was 13.8 per 100,000 population, more than triple the global target of 4.5.
Drug resistance and genetic mutations
The WHO warns of growing parasite resistance to key drugs. Additional challenges include genetic mutations in parasites that reduce the accuracy of rapid tests, resistance to pyrethroids in 48 countries, and the spread of the insecticide-resistant Anopheles stephensi mosquito in nine African countries. Climate change and extreme weather events are fueling new outbreaks, while conflict and instability are disrupting health systems.
Funding shortfall
Funding for malaria remains critically low: $3.9 billion was allocated in 2024, less than half the 2025 target. This funding cut has weakened health systems, led to the cancellation or postponement of routine screenings, and increased risk of drug supply disruptions.
"New tools give us hope, but we face significant challenges," said WHO Director-General Dr. Tedros Adhanom Ghebreyesus. The World Health Organization is calling on countries where malaria remains endemic to maintain their commitment to combating this dangerous disease.
What you need to know about malaria
Malaria is a life-threatening disease transmitted to humans by certain species of mosquitoes. It occurs primarily in tropical countries.
Infection occurs through a parasite bite. The disease is not transmitted from person to person.
Malaria symptoms range from mild to life-threatening. Mild symptoms include fever, chills, and headache. Severe symptoms include weakness, confusion, seizures, and difficulty breathing.
Infants, children under five years of age, pregnant women, and people with HIV infection or AIDS are at increased risk of severe infection.
Malaria can be prevented by avoiding mosquito bites and through medication. Treatment can help stop the further progression of mild cases.
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