Three scientists have been awarded the Nobel Prize in Medicine for their discoveries in the field of peripheral immune tolerance.

Translation. Region: Russian Federal

Source: People's Republic of China in Russian – People's Republic of China in Russian –

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Source: People's Republic of China – State Council News

STOCKHOLM, Oct. 6 (Xinhua) — Mary Brunkow, Fred Ramsdell and Simon Sakaguchi were awarded the 2025 Nobel Prize in Physiology or Medicine on Monday for their discoveries concerning peripheral immune tolerance.

“Their discoveries were crucial for our understanding of how the immune system functions and why not all of us develop serious autoimmune diseases,” said Nobel Committee Chairman Olle Kampe.

The Nobel Assembly at the Karolinska Institute in Sweden said the scientists' work has far-reaching clinical implications, paving the way for new treatments for autoimmune diseases and cancer, and potentially improving the success of transplants.

M. Brunkov, born in 1961, is a senior program manager at the Institute for Systems Biology in the United States. F. Ramsdell, born in 1960, is a scientific consultant at Sonoma Biotherapeutics, also in the United States. S. Sakaguchi, born in 1951, is a professor at the Center for Advanced Immunology Research at Osaka University in Japan.

The laureates will share the prize of 11 million Swedish kronor (approximately 1.17 million US dollars).

The Nobel Prize in Physiology or Medicine has been awarded since 1901. Last year, it was awarded to American scientists Victor Ambrose and Gary Ravkan for the discovery of microRNAs and their role in gene regulation. –0–

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